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While this methylation reaction was historically considered a relatively minor metabolic pathway for nicotinamide clearance, research over the past decade has revealed that NNMT plays a surprisingly important and previously underappreciated role in cellular energy metabolism, NAD+ homeostasis, adipocyte biology, and whole-body metabolic regulation

Zhao L, Jin L, Petrick JL et al (2023) Specific botanical groups of fruit and vegetable consumption and liver cancer and chronic liver disease mortality: a prospective cohort study

doi: 10.3390/ANTIBIOTICS11121785 81 IsolauriE.StasY.KankaanpP.ArvilommiH.SalminenS

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